ABSTRACT
La eficacia y seguridad del tratamiento homeopático fueron investigadas en niños con amigdalitis recurrente para la que se indicaba cirugía. Métodos: Estudio clínico prospectivo, aleatorizado, doble ciego, que incluyó 40 niños de entre 3 y 7 años de edad; 20 niños fueron tratados con medicación homeopática y otros 20 niños, con placebo. El seguimiento fue de 4 meses por niño. La evaluación de los resultados fue clínica mediante un cuestionario estándar y examen clínico el primer y último día de tratamiento. La amigdalitis recurrente se definió como ocurrencia de 5 a 7 episodios de amigdalitis bacteriana aguda al año. Resultados: Del grupo de 18 niños que completó el tratamiento homeopático, 14 no presentó episodio alguno de amigdalitis bacteriana aguda; del grupo de 15 niños que recibió placebo, 5 pacientes no presentaron amigdalitis. Esta diferencia fue estadísticamente significativa (p = 0,015). Ninguno de los pacientes presentó efectos secundarios. Conclusiones: El tratamiento homeopático fue efectivo en niños con amigdalitis recurrente, en comparación con el placebo; a 14 niños (78%) ya no se les indicó cirugía. El tratamiento homeopático no se asoció con eventos adversos.
The efficacy and safety of homeopathic treatment was investigated on children with recurrent tonsillitis justifying surgery. Methods: Prospective, randomized,double-blind clinical trial that included 40 children between ages of 3 to 7 years old;20 children were treated with homeopathic medication and 20 children with placebo. Follow up was 4 months per child. Assessment of results was clinical by means of a standard questionnaire and clinical examination on the first and last day of treatment.Recurrent tonsillitis was defined as 5 to 7 episodes of bacterial acute tonsillitis per year. Results: From the group of 18 children who completed homeopathic treatment, 14 did not present any episode of acute bacterial tonsillitis; from the group of 15 children whoreceived placebo 5 patients did not present tonsillitis; this difference was statistically significant (p= 0,015). None of the patient exhibited side effects. Conclusions: Homeopathic treatment was effective in children with recurrent tonsillitis compared to placebo, 14 children (78%) were no longer indicated surgery. Homeopathic treatment was not associated with adverse events.
Subject(s)
Humans , Child, Preschool , Child , Tonsillitis/drug therapy , Homeopathic Remedy , Double-Blind MethodABSTRACT
OBJECTIVE: The efficacy and safety of homeopathic treatment was investigated onchildren with recurrent tonsillitis justifying surgery. METHODS: Prospective, randomized, double-blind clinical trial that included 40 children between ages of 3 to 7 years old;20 children were treated with homeopathic medication and 20 children with placebo. Follow up was 4 months per child. Assessment of results was clinical by means of astandard questionnaire and clinical examination on the first and last day of treatment. Recurrent tonsillitis was defined as 5 to 7 episodes of bacterial acute tonsillitis per year. RESULTS: From the group of 18 children who completed homeopathic treatment, 14 did not present any episode of acute bacterial tonsillitis; from the group of 15 children who received placebo 5 patients did not present tonsillitis; this difference was statistically significant (p= 0,015). None of the patient exhibited side effects. CONCLUSIONS: Homeopathic treatment was effective in children with recurrent tonsillitis compared toplacebo, 14 children (78%) were no longer indicated surgery. Homeopathic treatment was not associated with adverse events.
Subject(s)
Male , Female , Humans , Child, Preschool , Child , Homeopathy , Tonsillitis/therapy , Lycopodium clavatum/therapeutic use , Pulsatilla nigricans/therapeutic use , Lachesis muta/therapeutic use , Atropa belladonna , /therapeutic use , /therapeutic useABSTRACT
OBJETIVO: Avaliar a eficácia e segurança do tratamento homeopático em crianças com adenóide obstrutiva, com indicaçäo cirúrgica. FORMA DE ESTUDO: Clínico prospectivo. Material e método: Estudo prospectivo, duplo-cego, randomizado, em que foram incluídas 40 crianças com idade variando de 3 a 7 anos, 20 crianças foram tratadas com medicaçäo homeopática individualizada (Simillimum), baseada no princípio da similitude e 20 crianças receberam placebo. Todas as crianças do grupo medicaçäo homeopática foram medicadas diariamente com Agraphis nutans 6 CH, Thuya 6 CH e Adenóide 21CH; e as do grupo placebo receberam diariamente medicamentos sem o princípio ativo. A duraçäo do estudo de cada paciente foi de 4 meses. A avaliaçäo dos resultados foi clínica, por meio de questionário padräo, de exame otorrinolaringológico e nasofaringoscopia direta com fibroscópio flexível, no primeiro e no último dia de tratamento. Utilizou-se como critério de inclusäo a adenóide que ocupou mais do que 70 por cento da luz coanal. RESULTADOS: Das 20 crianças tratadas com medicamento homeopático, 13 näo apresentaram alteraçäo no tamanho da adenóide nos exames nasofaringoscópicos e 7 tiveram diminuiçäo da adenóide; das 20 crianças que receberam placebo por 4 meses, 11 näo apresentaram alteraçöes no tamanho da adenóide, 4 tiveram diminuiçäo da adenóide e 5 crianças tiveram aumento. Näo houve diferença estatística significante entre os grupos (P= 0,069). Na avaliaçäo clínica da evoluçäo dos pacientes, dos 20 pacientes tratados com medicamento homeopático, 17 se mantiveram inalterados, com respiraçäo oral e ronco, um paciente melhorou, ficando sem ronco e dois foram curados, isto é, a respiraçäo alterou-se de oral para nasal e sem ronco. Dos 20 pacientes tratados com placebo, 17 pacientes se mantiveram inalterados, um paciente melhorou do ronco e dois foram curados, näo tendo havido diferença estatística significante entre os grupos (P>0,999). CONCLUSÖES: O tratamento homeopático näo foi eficaz nas crianças com adenóide obstrutiva, mantendo-se a indicaçäo cirúrgica em 85 por cento dos pacientes. O medicamento homeopático näo provocou eventos adversos nas crianças